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1

The Ethics of Research Involving Animals : A Review of the Nuffield Council on Bioethics Report from a Three Rs Perspective

Hendriksen, Coenraad F.M.

Journal:

Alternatives to laboratory animals : ATLA

Année:

2005

Langue:

english

Fichier:

PDF, 81 KB

english, 2005

2

Interlaboratory Validation of in vitro Serological Assay Systems to Assess the Potency of Tetanus Toxoid in Vaccines for Veterinary Use

Coenraad F.M. Hendriksen, Jacob Woltjes, Arnoud M. Akkermans, Johan W. van der Gun, Frits R. Marsman, Mirjam H. Verschure, Kees Veldman

Journal:

Année:

1994

Fichier:

PDF, 560 KB

1994

3

Three Rs approaches in the production and quality control of fish vaccines

Paul J. Midtlyng, Coenraad Hendriksen, Elisabeth Balks, Lukas Bruckner, Lawrence Elsken, Øystein Evensen, Kjetil Fyrand, Allison Guy, Marlies Halder, Penny Hawkins, Gunn Kisen, Anne Berit Romstad, Kir

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 234 KB

english, 2011

4

An in vitro immune response model to determine tetanus toxoid antigen (vaccine) specific immunogenicity: Selection of sensitive assay criteria

Sytse J. Piersma, Marlies P.P.A.M. Leenaars, Laurence Guzylack-Piriou, Artur Summerfield, Coenraad F.M. Hendriksen, Ken C. McCullough

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 406 KB

english, 2006

5

Immune responses and side effects of five different oil-based adjuvants in mice

Marlies Leenaars, Marianne A Koedam, Coenraad F.M Hendriksen, Eric Claassen

Journal:

Veterinary Immunology and Immunopathology

Année:

1998

Langue:

english

Fichier:

PDF, 257 KB

english, 1998

6

The Isolated Chicken Eye test to replace the Draize test in rabbits

Prinsen, Menk K., Hendriksen, Coenraad F.M., Krul, Cyrille A.M., Woutersen, Ruud A.

Journal:

Regulatory Toxicology and Pharmacology

Année:

2017

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2017

7

Are all motivation tests the same? The effect of two adaptations to a three-chamber consumer demand study in ferrets

Reijgwart, Marsinah L., Vinke, Claudia M., Hendriksen, Coenraad F.M., van der Meer, Miriam, Schoemaker, Nico J., van Zeeland, Yvonne R.A.

Journal:

Animal Behaviour

Année:

2018

Langue:

english

Fichier:

PDF, 581 KB

english, 2018

8

The Production of Avian (Egg Yolk) Antibodies: IgY

Schade, RÃ¼diger, Staak, Christian, Hendriksen, Coenraad, Erhard, Michael, Hugl, Herbert, Koch, Guus, Larsson, Anders, Pollmann, Wolfgang, van Regenmortel, Marc, Rijke, Eric, Spielmann, Horst, Steinbu

Journal:

Alternatives to laboratory animals : ATLA

Année:

1996

Fichier:

PDF, 751 KB

1996

9

Effects of subcutaneous versus intravenous administration of cyclosporin a on rat thymic histology and pharmacokinetics

Eric J. de Waal, Henk-Jan Schuurman, Coenraad Hendriksen, Bert Elvers, Aalt Van Dijk, Henk Van Loveren

Journal:

International Journal of Immunopharmacology

Année:

1992

Langue:

english

Fichier:

PDF, 718 KB

english, 1992

10

Development of Pertussis Serological Potency Test: Serological assessment of antibody response induced by whole cell vaccine as an alternative to mouse protection in an intracerebral challenge model

Arno van der Ark, Ineke van Straaten-van de Kappelle, Arnoud Akkermans, Coenraad Hendriksen, Huib van de Donk

Journal:

Année:

1994

Fichier:

PDF, 497 KB

1994

11

Collaborative Study on Test Systems to Assess Toxicity of Whole Cell Pertussis Vaccine

Ineke van Straaten-van de Kappelle, Johan W. van der Gun, Frits R. Marsman, Coenraad F.M. Hendriksen, Huib J.M. van de Donk

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 157 KB

english, 1997

12

The Pertussis Serological Potency Test Collaborative Study to Evaluate Replacement of the Mouse Protection Test

Arno van der Ark, Ineke van Straaten-van de Kappelle, Rose-Marie Ölander, Karlheinz Enssle, Suresh Jadhav, Huib van de Donk, Coenraad Hendriksen

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 141 KB

english, 2000

13

Ultrastructure of hepatic angiosarcoma in rats induced by vinyl chloride

Benjamin J. Spit, Victor J. Feron, Coenraad F.M. Hendriksen

Journal:

Experimental and Molecular Pathology

Année:

1981

Langue:

english

Fichier:

PDF, 3.63 MB

english, 1981

14

Handling effects on body weight and behaviour of group-housed male rabbits in a laboratory setting

Cynthia M. Verwer, Geert van Amerongen, Ruud van den Bos, Coenraad F.M. Hendriksen

Journal:

Applied Animal Behaviour Science

Année:

2009

Langue:

english

Fichier:

PDF, 547 KB

english, 2009

15

The consistency approach for the quality control of vaccines

Coenraad Hendriksen, Juan L. Arciniega, Lukas Bruckner, Michel Chevalier, Emmanuelle Coppens, Johan Descamps, Michel Duchêne, David Michael Dusek, Marlies Halder, Hans Kreeftenberg, Alexandrine Maes,

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 141 KB

english, 2008

16

Application of the Three Rs to challenge assays used in vaccine testing: Tenth report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement

Maggy Jennings, David B. Morton, Emmanuelle Charton, Jane Cooper, Coenraad Hendriksen, Stella Martin, Michael C. Pearce, Scott Price, Keith Redhead, Nick Reed, Hugh Simmons, Stephen Spencer, Hilary Wi

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 213 KB

english, 2010

17

The consistency approach for quality control of vaccines – A strategy to improve quality control and implement 3Rs

Fabrizio De Mattia, Jean-Michel Chapsal, Johan Descamps, Marlies Halder, Nicholas Jarrett, Imke Kross, Frederic Mortiaux, Cecile Ponsar, Keith Redhead, Jo McKelvie, Coenraad Hendriksen

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 153 KB

english, 2011

18

In vivo pertussis toxin treatment reduces contraction of rat resistance arteries but not that of mouse trachea

Cornelia E. van Meijeren, Wim Vleeming, Ton van de Kuil, Javotte Manni, Diane Kegler, Coenraad F.M. Hendriksen, Dick J. de Wildt

Journal:

European Journal of Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 352 KB

english, 2004

19

Pertussis toxin-induced histamine sensitisation: an aspecific phenomenon independent from the nitric oxide system?

Cornelia E. van Meijeren, Wim Vleeming, Ton van de Kuil, Anne-Loes Gerards, Coenraad F.M. Hendriksen, Dick J. de Wildt

Journal:

European Journal of Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 560 KB

english, 2004

20

Pertussis toxin relaxes small arteries with no vascular lesions or vascular smooth muscle cell injury

Cornelia E. van Meijeren, Wim Vleeming, Jan A.M.A. Dormans, Ton van de Kuil, Antoon Opperhuizen, Coenraad F.M. Hendriksen, Dick J. de Wildt

Journal:

Experimental and Toxicologic Pathology

Année:

2004

Langue:

english

Fichier:

PDF, 570 KB

english, 2004

21

lacZ mouse embryonic fibroblasts detect both clastogens and mutagens

Anuska G. Mahabir, Edwin Zwart, Mirjam Schaap, Jan van Benthem, Annemieke de Vries, Lya G. Hernandez, Coenraad F.M. Hendriksen, Harry van Steeg

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

2009

Langue:

english

Fichier:

PDF, 890 KB

english, 2009

22

Effects of housing condition on experimental outcome in a reproduction toxicity study

Cynthia M. Verwer, Leo T.M. van der Ven, Ruud van den Bos, Coenraad F.M. Hendriksen

Journal:

Regulatory Toxicology and Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 343 KB

english, 2007

23

Comparison of clastogen-induced gene expression profiles in wild-type and DNA repair-deficientRad54/Rad54Bcells

Anuska G Mahabir, Mirjam M Schaap, Jeroen LA Pennings, Jan van Benthem, Coenraad FM Hendriksen, Harry van Steeg

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 517 KB

english, 2010

24

Workshop on Animal free Detection of Pertussis Toxin in Vaccines – Alternatives to the Histamine Sensitisation Test

Christina Bache, Marieke Hoonakker, Coenraad Hendriksen, Karl-Heinz Buchheit, Ingo Spreitzer, Thomas Montag

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 102 KB

english, 2012

25

The cAMP assay: A functional in vitro alternative to the in vivo Histamine Sensitization test

Marieke E. Hoonakker, Nicole Ruiterkamp, Coenraad F.M. Hendriksen

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 404 KB

english, 2010

26

Reduction of animal use in human vaccine quality control: opportunities and problems

Bernard Metz, Coenraad.F.M Hendriksen, Wim Jiskoot, Gideon F.A Kersten

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 497 KB

english, 2002

27

Replacement, reduction and refinement alternatives to animal use in vaccine potency measurement

Hendriksen, Coenraad FM

Journal:

Expert Review of Vaccines

Année:

2009

Langue:

english

Fichier:

PDF, 317 KB

english, 2009

28

Humane endpoints in vaccine potency testing

Hendriksen, Coenraad F.M.

Journal:

Procedia in Vaccinology

Année:

2011

Langue:

english

Fichier:

PDF, 443 KB

english, 2011

29

Alternative methods and strategies to reduce, refine, and replace animal use for human vaccine post-licensing safety testing: state of the science and future directions

Isbrucker, Richard, Levis, Robin, Casey, Warren, McFarland, Richard, Schmitt, Michael, Arciniega, Juan, Descamps, Johan, Finn, Theresa, Hendriksen, Coenraad, Horiuchi, Yoshinobu, Keller, James, Kojima

Journal:

Procedia in Vaccinology

Année:

2011

Langue:

english

Fichier:

PDF, 449 KB

english, 2011

30

Improving animal welfare and reducing animal use for human vaccine potency testing: state of the science and future directions

Casey, Warren, Schmitt, Michael, McFarland, Richard, Isbrucker, Richard, Levis, Robin, Arciniega, Juan, Descamps, Johan, Finn, Theresa, Hendriksen, Coenraad, Horiuchi, Yoshinobu, Keller, James, Kojima

Journal:

Procedia in Vaccinology

Année:

2011

Langue:

english

Fichier:

PDF, 368 KB

english, 2011

31

Structural perturbation of diphtheria toxoid upon adsorption to aluminium hydroxide adjuvant

Marie Régnier, Bernard Metz, Wichard Tilstra, Coenraad Hendriksen, Wim Jiskoot, Willem Norde, Gideon Kersten

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 606 KB

english, 2012

32

DNA-repair-deficient Rad54/Rad54B mice are more sensitive to clastogens than wild-type mice

Anuska G. Mahabir, Mirjam Schaap, Peter Theunissen, Jan van Benthem, Jeroen Essers, Annemieke de Vries, Coenraad F.M. Hendriksen, Harry van Steeg

Journal:

Toxicology Letters

Année:

2008

Langue:

english

Fichier:

PDF, 546 KB

english, 2008

33

Physicochemical and immunochemical assays for monitoring consistent production of tetanus toxoid

Metz, Bernard, Tilstra, Wichard, van der Put, Robert, Spruit, Nanda, van den IJssel, Jan, Robert, Jolanda, Hendriksen, Coenraad, Kersten, Gideon

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 515 KB

english, 2013

34

Effects of Environmental Enrichment for Mice: Variation in Experimental Results

Van de Weerd, Heleen A., Aarsen, Emma L., Mulder, Anne, Kruitwagen, Cas L. J. J., Hendriksen, Coenraad F. M., Baumans, Vera

Journal:

Journal of Applied Animal Welfare Science

Année:

2002

Langue:

english

Fichier:

PDF, 268 KB

english, 2002

35

Replacing the NIH test for rabies vaccine potency testing: A synopsis of drivers and barriers

Schiffelers, Marie-Jeanne, Blaauboer, Bas, Bakker, Wieger, Hendriksen, Coenraad

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 549 KB

english, 2014

36

Regulatory acceptance and use of 3R models for pharmaceuticals and chemicals: Expert opinions on the state of affairs and the way forward

Schiffelers, Marie-Jeanne W.A., Blaauboer, Bas J., Bakker, Wieger E., Beken, Sonja, Hendriksen, Coenraad F.M., Koëter, Herman B.W.M., Krul, Cyrille

Journal:

Regulatory Toxicology and Pharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 594 KB

english, 2014

37

Laboratory Animals in Vaccine Production and Control || Opportunities for Replacement, Reduction or Refinement: Poultry Vaccines

Hendriksen, Coenraad F. M.

Année:

1988

Langue:

english

Fichier:

PDF, 1.02 MB

english, 1988

38

Regulatory acceptance and use of the Extended One Generation Reproductive Toxicity Study within Europe

Schiffelers, Marie-Jeanne W.A., Blaauboer, Bas J., Bakker, Wieger E., Hendriksen, Coenraad F.M., Krul, Cyrille

Journal:

Regulatory Toxicology and Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 606 KB

english, 2015

39

Ferrets’ (Mustela putorius furo) enrichment priorities and preferences as determined in a seven-chamber consumer demand study

Reijgwart, Marsinah L., Vinke, Claudia M., Hendriksen, Coenraad F.M., van der Meer, Miriam, Schoemaker, Nico J., van Zeeland, Yvonne R.A.

Journal:

Applied Animal Behaviour Science

Année:

2016

Langue:

english

Fichier:

PDF, 991 KB

english, 2016

40

Workaholic ferrets: Does a two-chamber consumer demand study give insight in the preferences of laboratory ferrets (Mustela putorius furo)?

Reijgwart, Marsinah L., Vinke, Claudia M., Hendriksen, Coenraad F.M., van der Meer, Miriam, Schoemaker, Nico J., van Zeeland, Yvonne R.A.

Journal:

Applied Animal Behaviour Science

Année:

2015

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2015

41

Reporter cell lines for detection of pertussis toxin in acellular pertussis vaccines as a functional animal-free alternative to the in vivo histamine sensitization test

Hoonakker, Marieke E., Verhagen, Lisa M., van der Maas, Larissa, Sloots, Arjen, Hendriksen, Coenraad F.M.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 3.45 MB

english, 2017

42

Antigenic fingerprinting of diphtheria toxoid adsorbed to aluminium phosphate

Westdijk, Janny, Metz, Bernard, Spruit, Nanda, Tilstra, Wichard, van der Gun, Johan, Hendriksen, Coenraad, Kersten, Gideon

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 412 KB

english, 2017

43

Safety testing of acellular pertussis vaccines: use of animals and 3Rs alternatives

Hoonakker, Marieke, Arciniega, Juan, Hendriksen, Coenraad

Journal:

Human Vaccines & Immunotherapeutics

Année:

2017

Langue:

english

Fichier:

PDF, 981 KB

english, 2017

44

An explorative study on the effect of provision of preferred and non-preferred enrichment on behavioural and physiological parameters in laboratory ferrets ( Mustela putorius furo )

Reijgwart, Marsinah L., Vinke, Claudia M., Hendriksen, Coenraad F.M., den Hoed, Kim M., van der Meer, Manon I., van der Meer, Miriam, Schoemaker, Nico J., van Zeeland, Yvonne R.A.

Journal:

Applied Animal Behaviour Science

Année:

2018

Langue:

english

Fichier:

PDF, 742 KB

english, 2018

45

Vaccine-Mediated Activation of Human TLR4 Is Affected by Modulation of Culture Conditions during Whole-Cell Pertussis Vaccine Preparation

Hoonakker, Marieke E., Verhagen, Lisa M., Pupo, Elder, de Haan, Alex, Metz, Bernard, Hendriksen, Coenraad F. M., Han, Wanda G. H., Sloots, Arjen, Miyaji, Eliane Namie

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2016

46

Reduction Strategies in Animal Research: A Review of Scientific Approaches at the Intra-experimental, Supra-experimental and Extra-experimental Levels

de Boo, Jasmijn, Hendriksen, Coenraad

Journal:

Alternatives to laboratory animals : ATLA

Année:

2005

Langue:

english

Fichier:

PDF, 102 KB

english, 2005

47

New Techniques for Producing Transgenic Animals — a Mixed Blessing from Both the Scientific and Animal Welfare Perspectives

Hendriksen, Coenraad, Spielmann, Horst

Journal:

Alternatives to laboratory animals : ATLA

Année:

2014

Langue:

english

Fichier:

PDF, 45 KB

english, 2014

48

New Techniques for Producing Transgenic Animals — a Mixed Blessing from Both the Scientific and Animal Welfare Perspectives

Hendriksen, Coenraad, Spielmann, Horst

Journal:

Alternatives to laboratory animals : ATLA

Année:

2014

Fichier:

PDF, 45 KB

2014

49

Animals are More than Tools

Hendriksen, Coenraad, Baumans, Vera, Blaauboer, Bas

Journal:

Alternatives to laboratory animals : ATLA

Année:

2012

Langue:

english

Fichier:

PDF, 26 KB

english, 2012

50

Reduction of Numbers of Animals Used in the Quality Control of Biologicals

Hendriksen, Coenraad F.M.

Journal:

Alternatives to laboratory animals : ATLA

Année:

2004

Langue:

english

Fichier:

PDF, 90 KB

english, 2004